Medicine

Advancing ASO treatments coming from progression to execution

.Competing passions.R.S., M.S., H.G. and also A.A.R. are actually coordinators of the 1M1M campaign. H.G. and A.A.R. are panel of directors members and also R.S., M.S. as well as A.A.R. are actually members of the scientific advisory board of N1C. A.A.R. makes known job through LUMC, which has patents on exon-skipping modern technology, several of which has been accredited to BioMarin as well as consequently sublicensed to Sarepta. As co-inventor of a number of these patents, A.A.R. was actually entitled to an allotment of nobilities. A.A.R. further discloses acting as professional for PTC Rehabs, Sarepta Rehabs, Regenxbio, Dyne Rehabs, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and also Astra Zeneca. Previously 5 years, A.A.R. additionally did impromptu consulting with for Alpha Anomeric. A.A.R. likewise discloses registration of the clinical boards of advisers of Eisai, Hybridize Rehabs, Silence Rehabs, Sarepta Therapeutics, Sapreme as well as Mitorx. In the past 5 years, A.A.R. was actually also a medical advisory board participant for ProQR. Remuneration for A.A.R. u00e2 s consulting and recommending activities is actually spent to LUMC. Before 5 years, LUMC additionally acquired speaker honoraria from PTC Therapeutics, Alnylam Netherlands, Italfarmaco and also Pfizer and moneying for contract research study coming from Sapreme, Eisai, Galapagos, Synaffix and also Alpha Anomeric. Job backing is obtained from Sarepta Therapeutics and also Entrada using unlimited gives. H.G. possesses nothing at all to disclose relative to the topics dealt with in this document. Over the last 5 years, he has additionally gotten consultancy honoraria coming from UCB. M.S. received consultancy honoraria from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly as well as Solaxa before 5 years, all irrelevant to today manuscript. R.S. possesses nothing to reveal in connection with the subjects covered in this particular composition. She has acquired sound speaker and/or consultancy honoraria or even sponsoring contributions from Abbvie, Bial, STADA and also Everpharma in the past 5 years.

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